Insulator Protein Helps Organize the Gaps in the Axon's Insulation
نویسنده
چکیده
The protein P0 has long been known to play a crucial role in holding together the myelin sheath that insulates peripheral nerves. A new study reveals that P0 is also important for organizing the nodes of Ranvier that occupy the gaps in the insulation. Read the Research Article.
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Insulation of enhancer-promoter communication by a gypsy transposon insert in the Drosophila cut gene: cooperation between suppressor of hairy-wing and modifier of mdg4 proteins.
The Drosophila mod(mdg4) gene products counteract heterochromatin-mediated silencing of the white gene and help activate genes of the bithorax complex. They also regulate the insulator activity of the gypsy transposon when gypsy inserts between an enhancer and promoter. The Su(Hw) protein is required for gypsy-mediated insulation, and the Mod(mdg4)-67.2 protein binds to Su(Hw). The aim of this ...
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